PT-141

High-Purity PT-141 (Bremelanotide) 10mg for Advanced Melanocortin Receptor & Central Nervous System Research

Product Note: This product is intended strictly for laboratory and scientific research purposes. It is not for human or veterinary use. All research procedures must be conducted in controlled laboratory environments by qualified professionals.

PT-141 (Bremelanotide) is a synthetic cyclic lactam peptide derivative of the alpha-melanocyte-stimulating hormone ($\alpha$-MSH). Unlike traditional peripheral agents, PT-141 acts primarily as an agonist on central melanocortin receptors (specifically MC3R and MC4R) within the central nervous system. In experimental models, it has been heavily investigated for its unique role in activating neural circuits related to arousal, motivation, and homeostatic behavioral pathways.

Supplied as a vacuum-sealed, sterile lyophilized (freeze-dried) powder pellet in a clear glass vial, this format ensures long-term chemical stability and high purity. Each individual vial contains precisely 10mg of PT-141, verified via rigorous high-performance liquid chromatography (HPLC) analysis.

Key Research Areas:

• Investigation of central melanocortin receptor signaling pathways (MC3R and MC4R) in behavioral and neurological models.

• Studies regarding central nervous system regulation of arousal and physiological motivation.

• Evaluation of cyclic peptide structural stability and blood-brain barrier permeability assays.

• Advanced biochemical assays exploring neuroendocrine modulation and receptor binding affinity.

Technical Specifications:

• Peptide Identity: PT-141 (Bremelanotide)

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (Cyclic lactam analog)

• Molecular Formula: C50H68N14O10

• Molecular Weight: ~1025.15 g/mol

• Purity: >= 99% (HPLC verified)

• Quantity: 10 mg

• Format: White Lyophilized Powder

Storage and Handling:

Store the lyophilized powder at -20°C (freezer) for long-term preservation or between 2°C to 8°C (refrigerator) for short-term use. Keep protected from direct light and moisture. Reconstitute strictly using sterile or bacteriostatic water for immediate laboratory testing.